| Adams-Crocker-Fish House | Barnstable | Building | 1987 |
| Ahearn House and Summer House | Wellfleet | Building | 1984 |
| Ames, Josiah A., House | Barnstable | Building | 1987 |
| Ancient Burying Ground | Barnstable | Site | 1987 |
| Aptucxet Trading Post Museum Historic District | Bourne | District | 2021 |
| Atwood-Higgins Historic District | Wellfleet | District | 2010 |
| Atwood, Thomas, House | Wellfleet | Building | 1976 |
| Avant House | Mashpee | Building | 1998 |
| Baker, Benjamin, Jr., House | Barnstable | Building | 1987 |
| Baker, Capt. Seth, Jr., House | Barnstable | Building | 1987 |
| Baker, Nathaniel, House | Barnstable | Building | 1987 |
| Barnstable County Courthouse | Barnstable | Building | 1981 |
| Baxter Mill | West Yarmouth | Building | 1981 |
| Baxter, Capt. Rodney J., House | Barnstable | Building | 1987 |
| Baxter, Capt. Sylvester, House | Barnstable | Building | 1987 |
| Baxter, Charles L., House | Barnstable | Building | 1987 |
| Baxter, Shubael, House | Barnstable | Building | 1987 |
| Beacon, The | Eastham | Structure | 1987 |
| Bearse, Capt. Allen H., House | Barnstable | Building | 1987 |
| Bearse, Capt. Oliver, House | Barnstable | Building | 1987 |
| Berry, Captain James, House | Harwich | Building | 1986 |
| Blish-Garret House | Barnstable | Building | 1987 |
| Bourne High School | Bourne | Building | 2013 |
| Bourne Town Hall | Bourne | Building | 2013 |
| Bourne, Jonathan, Public Library | Bourne | Building | 2013 |
| Bournedale Village School | Bourne | Building | 2013 |
| Brandeis, Louis, House NHL | Chatham | Building | 1972 |
| Bray, Thomas, Farm | Yarmouth | Building | 1988 |
| Brewster Old King's Highway Historic District | Brewster | District | 1996 |
| Brick Block | Chatham | Building | 1979 |
| Bridge Road Cemetery | Eastham | Site | 1999 |
| Briggs, George I., House | Bourne | Building | 1981 |
| Building at 237-239 Main Street | Barnstable | Building | 1987 |
| Building at 600 Main Street | Barnstable | Building | 1987 |
| Building at 606 Main Street | Barnstable | Building | 1987 |
| Building at 614 Main Street | Barnstable | Building | 1987 |
| Campbell, Collen C., House | Barnstable | Building | 1987 |
| Canary-Hartnett House | Barnstable | Building | 1987 |
| Cataumet Schoolhouse | Bourne | Building | 2019 |
| Center Methodist Church | Provincetown | Building | 1975 |
| Centerville Historic District | Barnstable | District | 1987 |
| Central Fire Station | Falmouth | Building | 1998 |
| Chase Library | Harwich | Building | 2014 |
| Chase, Lemuel B., House | Barnstable | Building | 1987 |
| Chatham Light Station | Chatham | Structure | 1987 |
| Chatham Railroad Depot | Chatham | Building | 1978 |
| Chatham Windmill | Chatham | Structure | 1978 |
| Cleveland Ledge Light Station | Bourne | Structure | 1987 |
| Coast Guard Motor Lifeboat CG 36500 | Orleans | Structure | 2005 |
| Cobb Memorial Library | Truro | Building | 2013 |
| Collins Cottages Historic District | Eastham | District | 1999 |
| Cotuit Historic District | Barnstable | District | 1987 |
| Cove Burying Ground | Eastham | Site | 1999 |
| Craigville Historic District | Barnstable | District | 1987 |
| Crocker, Benomi and Barnabas, House | Barnstable | Building | 1987 |
| Crocker, Capt. Alexander, House | Barnstable | Building | 1987 |
| Crocker, Ebenezer, Jr., House | Barnstable | Building | 1987 |
| Crocker, Lot, House | Barnstable | Building | 1987 |
| Crosby, Daniel, House | Barnstable | Building | 1987 |
| Crowell-Bourne Farm | West Falmouth | Building | 1980 |
| Crowell-Smith House | Barnstable | Building | 1987 |
| Dennis Village Cemetery | Dennis | Site | 2005 |
| Dennis, Josiah, House | Dennis | Building | 1974 |
| Dillingham House | Brewster | Building | 1976 |
| Dune Shacks of Peaked Hill Bars Historic District | Provincetown | District | 2012 |
| Eastham Center Historic District | Eastham | District | 1999 |
| Eldredge Public Library | Chatham | Building | 1992 |
| Falmouth Pumping Station | Falmouth | Building | 1998 |
| Falmouth Village Green Historic District | Falmouth | District | 1996 |
| First Congregational Parish Historic District | Truro | District | 2014 |
| First Universalist Chruch | Provincetown | Building | 1972 |
| Forestdale School | Sandwich | Building | 1997 |
| Fort Hill Rural Historic District | Eastham | District | 2001 |
| French Cable Hut | North Eastham | Building | 1976 |
| French Cable Station | Orleans | Building | 1972 |
| Fuller House | Barnstable | Building | 1987 |
| Gifford Farm | Barnstable | Building | 1987 |
| Gleason, Dr. Edward Francis, House | Barnstable | Building | 1987 |
| Goodspeed House | Barnstable | Building | 1987 |
| Gray, Capt. Thomas, House | Barnstable | Building | 1987 |
| Half Way House | Chatham | Building | 1978 |
| Hallett, Capt. William, House | Barnstable | Building | 1987 |
| Hallett, Seth, House | Barnstable | Building | 1987 |
| Harlow Homestead | Barnstable | Building | 1987 |
| Harwich Historic District | Harwich | District | 1975 |
| Harwich Port Library | Harwich | Building | 2026 |
| Hatch, Ruth and Robert Jr., House | Wellfleet | Building | 2014 |
| Hawley, Gideon, House | Barnstable | Building | 1987 |
| Hawthorne Class Studio | Provincetown | Building | 1978 |
| Higgins, Jedediah, House | North Truro | Structure | 1984 |
| Highland House | Truro | Building | 1975 |
| Highland Light Station | Truro | Structure | 1987 |
| Hinckley Homestead | Barnstable | Building | 1987 |
| Hinckley, Capt. Joseph, House | Barnstable | Building | 1987 |
| Hinckley, Nymphus, House | Barnstable | Building | 1987 |
| Hinckley, S. Alexander, House | Barnstable | Building | 1987 |
| Hinckley's Corner Historic District | WellFleet | District | 1998 |
| Hyannis Port Historic District | Barnstable | District | 1987 |
| Hyannis Road Historic District | Barnstable | District | 1987 |
| Isham, Herman, House | Barnstable | Building | 1987 |
| Jarves, John and Mary Waterman, House | Sandwich | Building | 2002 |
| Jarvesville Historic District | Sanwich | District | 2010 |
| Jenkins-Whelden Farmstead | Barnstable | Building | 1987 |
| Jenkins, John, Homestead | Barnstable | Building | 1987 |
| Jenkins, Joseph, House | Barnstable | Building | 1987 |
| Kelley, Mercelia Evelyn Eldridge, House | Chatham | Building | 2005 |
| Kennedy Compound NHL | Hyannis Port | District | 1972 |
| Kugel, Peter, House | Wellfleet | Building | 2014 |
| Kuhn, Samuel and Minette, House | Wellfleet | Building | |
| Lawrence Academy | Falmouth | Building | 1998 |
| Liberty Hall | Barnstable | Building | 1987 |
| Lincoln House Club | Barnstable | Building | 1987 |
| Long Point Light Station | Provincetown | Structure | 1987 |
| Lovell, Capt. George, House | Barnstable | Building | 1987 |
| Lovell, Nehemiah, House | Barnstable | Building | 1987 |
| Marcel Breuer House and Studio | Wellfleet | Building | 2024 |
| Marconi Wireless Station Site | South Wellfleet | Site | 1975 |
| Marconi-RCA Wireless Receiving Station | Chatham | District | 1994 |
| Marston, William, House | Barnstable | Building | 1987 |
| Marstons Mills Hearse House and Cemetery | Barnstable | Site | 1987 |
| Merrill Estate | Barnstable | Building | 1987 |
| Methodist Church | Barnstable | Building | 1987 |
| Mill Way Historic District | Barnstable | District | 1987 |
| Monomoy Point Lighthouse | Chatham | Building | 1979 |
| Municipal Group Historic District | Barnstable | District | 1987 |
| Nauset Archeological District NHL | Eastham | District | 1993 |
| Nauset Beach Light | Eastham | Structure | 1987 |
| Newcomb, John, House | Wellfleet | Building | 1988 |
| Nickerson Mansion | Brewster | Building | 1986 |
| Nobska Point Light Station | Falmouth | Structure | 1987 |
| North Falmouth Village Historic District | Falmouth | District | 1998 |
| Northside Historic District | Yarmouth | District | 1987 |
| Nye, Benjamin, Homestead | Sandwich | Building | 1992 |
| Nye, Elnathan, House | Falmouth | Building | 2002 |
| Oak Grove Cemetery | Falmouth | Site | 2014 |
| Old Harbor U.S. Life Saving Station | Chatham | Building | 1975 |
| Old Higgins Farm Windmill | Brewster | Structure | 1975 |
| Old Indian Meeting House | Mashpee | Building | 1998 |
| Old Jail | Barnstable | Building | 1971 |
| Old King's Highway Historic District | Barnstable | District | 1987 |
| Old North Cemetery | Truro | Site | 2013 |
| Old Town Center Historic District | Eastham | District | 2001 |
| Old Village Historic District | Chatham | District | 2001 |
| Osterville Baptist Church | Barnstable | Building | 1987 |
| Paine Hollow Road South Historic District | Wellfleet | District | 1998 |
| PAUL PALMER (Shipwreck and Remains) | Provincetown | Site | 2007 |
| Penniman, Edward, House and Barn | Eastham | Building | 1976 |
| Phinney, William and Jane, House | Barnstable | Building | 1987 |
| Pine Grove Cemetery | Truro | Site | 2013 |
| Pleasant-School Street Historic District | Barnstable | District | 1987 |
| Pond Hill School | Wellfleet | Building | 1989 |
| Poor House and Methodist Cemetery | Falmouth | Building | 1998 |
| Port Royal House | Chatham | Building | 1982 |
| Provincetown Historic District | Provincetown | District | 1989 |
| Provincetown Public Library | Provincetown | Building | 1975 |
| Race Point Light Station | Provincetown | Structure | 1987 |
| Rhodehouse, Nelson, House | Barnstable | Building | 1987 |
| Richardson, John, House | Barnstable | Building | 1987 |
| Robbins, Joseph, House | Barnstable | Building | 1987 |
| Round House | Barnstable | Building | 1987 |
| Rowell House | Wellfleet | Building | 1988 |
| Sampson's Folly-Josiah Sampson House | Barnstable | Building | 1987 |
| Sandy Neck Cultural Resources District | Barnstable | District | 1987 |
| Santuit Historic District | Barnstable | District | 1987 |
| Santuit Post Office | Barnstable | Building | 1987 |
| Saunders-Paine House | Wellfleet | Building | 1998 |
| Sea Call Farm | Orleans | Building | 2008 |
| Sears, Jacob, Memorial Library | Dennis | Building | 2009 |
| Sirna, Anthony and Allison, Studio | Wellfleet | Building | 2014 |
| Smith, Matthias, House | Barnstable | Building | 1987 |
| Smith, Samuel, Tavern Site | Wellfleet | Site | 1977 |
| South Chatham Village Historic District | Chatham | District | 2022 |
| South Harwich Methodist Church | Harwich | Building | 1986 |
| South Yarmouth/Bass River Historic District | Yarmouth | District | 1990 |
| Spring Hill Historic District | Sandwich | District | 2010 |
| Stony Brook-Factory Village Historic District | Brewster | District | 2000 |
| Taylor-Bray Farm | Yarmouth | Building | 1993 |
| Teaticket School | Falmouth | Building | 2002 |
| Three Sisters of Nauset (Twin Lights) | Eastham | Structure | 1987 |
| Tisza, Vera and Laszlo, House | Wellfleet | Building | 2014 |
| Tobey, Josiah, House | Falmouth | Building | 1994 |
| Town Boundary Marker | Barnstable | Object | 1987 |
| Town Hall Square Historic District | Sandwich | District | 1975 |
| Town Hall Square Historic District Boundary Increase | Sandwich | District | 2010 |
| Town Line Boundary Marker | Barnstable | Object | 1987 |
| Town Line Boundary Marker | Barnstable | Object | 1987 |
| Townsend House | Wellfleet | Building | 1998 |
| Travelers Club | Bourne | Building | 2025 |
| Truro Highlands Historic District | Truro | District | 2011 |
| U.S. Customshouse | Barnstable | Building | 1975 |
| Union Hall | Truro | Building | 1997 |
| Universalist Society Meetinghouse | Orleans | Building | 1999 |
| US Post Office-Provincetown Main | Provincetown | Building | 1987 |
| Waquoit Historic District | Falmouth | District | 2004 |
| Weeks, Barzillai, House | Barnstable | Building | 1987 |
| Weidlinger, Paul and Madeleine | Wellfleet | Building | 2014 |
| Wellfleet Center Historic District | Wellfleet | District | 1989 |
| West Barnstable Village-Meetinghouse Way Historic District | Barnstable | District | 1987 |
| West Dennis Graded School | Dennis | Building | 2000 |
| West Falmouth Village Historic District | Falmouth | District | 1998 |
| West Schoolhouse | Dennis | Building | 1975 |
| Whitman, Josiah B., House | Barnstable | Building | 1987 |
| Wianno Club | Osterville | Building | 1979 |
| Wianno Historic District | Barnstable | District | 1987 |
| Wing Fort House | East Sandwich | Building | 1976 |
| Wing's Neck Light | Bourne | Structure | 1987 |
| Wood End Light Lookout Station | Provincetown | Structure | 1987 |
| Yarmouth Camp Ground Historic District | Yarmouth/Barnstable | District | 1990 |
Brandeis, Louis, House NHL Chatham · Building · listed 1972 
Kennedy Compound NHL Hyannis Port · District · listed 1972 
Nauset Archeological District NHL Eastham · District · listed 1993 
Adams-Crocker-Fish House Barnstable · Building · listed 1987 
Ahearn House and Summer House Wellfleet · Building · listed 1984 
Ames, Josiah A., House Barnstable · Building · listed 1987 
Ancient Burying Ground Barnstable · Site · listed 1987 
Atwood, Thomas, House Wellfleet · Building · listed 1976 
Avant House Mashpee · Building · listed 1998 
Baker, Benjamin, Jr., House Barnstable · Building · listed 1987