| Americanization School | Oceanside | Building | 1994 |
| Anza Borrego-Palo Verde Site, S-2 | Borrego Springs | Site | 1985 |
| Anza Borrego-Sin Nombre, S-4 | Borrego Springs | Site | 1985 |
| Anza Borrego-Spit Mountain Site, S-3 | Borrego Springs | Site | 1985 |
| Arnold and Choates Addition-North Florence Heights Historic District (Additional Documentation) | San Diego | District | 2024 |
| Baker, Pearl, Row House | Rancho Santa Fe | Building | 1993 |
| Balboa Park NHL | San Diego | District | 1977 |
| Balboa Theatre | San Diego | Building | 1996 |
| Bancroft, Hubert H., Ranchhouse NHL | Spring Valley | Building | 1966 |
| Bandy House | Escondido | Building | 1993 |
| Beach, A.H., House | Escondido | Building | 1993 |
| Bear Valley Archeological Site | Pine Valley | Site | 1974 |
| Beardsley, John R. and Florence Porterfield, House | San Diego | Building | 2011 |
| BERKELEY NHL | San Diego | Structure | 1990 |
| Bingham, Samuel, House | Rancho Santa Fe | Building | 1991 |
| Bishop, Ellis, House | Rancho Santa Fe | Building | 1999 |
| Black, William, House-SDM-W-12 Locus A (CA-SDI-4669) | La Jolla | Site | 2008 |
| Brawn, Charles A., House | Vista | Building | 1986 |
| Brick Row | National City | Building | 1973 |
| Bumann Ranch | Encinitas | Building | 2020 |
| Burnham-Marston House | San Diego | Building | 1986 |
| CABRILLO (Ferry) | San Diego | Structure | 2025 |
| Cabrillo National Monument | San Diego | District | 1966 |
| California Quadrangle | San Diego | Building | 1974 |
| Canfield-Wright House | Del Mar | Building | 2004 |
| Carlsbad Santa Fe Depot | Carlsbad | Building | 1993 |
| Carmichael, Norman and Florence B., House | Rancho Santa Fe | Building | 1991 |
| Case Study House No. 23C | La Jolla | Building | 2013 |
| Castle, The | Ramona | Building | 1978 |
| Chaplain's House | San Diego | Building | 1978 |
| Chicano Park NHL | San Diego | Site | |
| Chicano Park | San Diego | Site | 2013 |
| Christiancy, George A. C., House | Rancho Santa Fe | Building | 1991 |
| City of San Diego Police Headquarters, Jails and Courts | San Diego | Building | 1998 |
| Clotfelter, Reginald M. and Constance, Row House | Rancho Santa Fe | Building | 1991 |
| Coulter House | San Diego | Building | 1983 |
| Cuyamaca Village | San Diego | Site | 2008 |
| Eagles Hall | San Diego | Building | 1985 |
| Edgemoor Farm Dairy Barn | Santee | Building | 1985 |
| El Cortez Apartment Hotel | San Diego | Building | 2002 |
| El Prado Complex | San Diego | District | 1976 |
| Encinitas Boathouses | Encinitas | Building | 2019 |
| Estudillo House NHL | San Diego | Building | 1970 |
| Fages-De Anza Trail-Southern Emigrant Road | Borrego Springs | District | 1973 |
| Felicita County Park Prehistoric Village Site | Escondido | Site | 2008 |
| Fleming, Guy and Margaret, House | San Diego | Building | 1998 |
| Ford Building | San Diego | Building | 1973 |
| Fort Rosecrans National Cemetery | San Diego | District | 2016 |
| Gaslamp Quarter Historic District | San Diego | District | 1980 |
| Georgia Street Bridge-Caltrans Bridge | San Diego | Structure | 1999 |
| Ginty, John, House | San Diego | Building | 2006 |
| Grand-Horton Hotel | San Diego | Building | 1980 |
| Granger Hall | National City | Building | 1975 |
| Grant, U.S. Hotel | San Diego | Building | 1979 |
| Haines, Alfred, House | San Diego | Building | 1992 |
| Hawthorne Inn | San Diego | Building | 1982 |
| Heart of Bankers Hill Historic District | San Diego | District | 2024 |
| Heilman Villas | Coronado | District | 1992 |
| Holzwasser-Walker Scoot Building and Owl Drug Building | San Diego | Building | 2005 |
| Hotel Charlotta | Escondido | Building | 1993 |
| Hotel Del Coronado NHL | Coronado | Building | 1971 |
| Howell House | Escondido | Building | 1992 |
| Independent Order of Odd Fellows Building | San Diego | Building | 1978 |
| Initial Point of Boundary Between U.S. and Mexico | San Diego | Site | 1974 |
| Inspiration Heights Historic District | San Diego | District | 2021 |
| Institute of Geophysics and Planetary Physics | La Jolla | Building | 2021 |
| Johnson-Taylor Ranch Headquarters | San Diego | Building | 1980 |
| Kinsey, Martha, House | La Jolla | Building | 1992 |
| Kuchamaa | Tecate | District | 1992 |
| Kwaaymii Homeland | Mount Laguna | Site | 2015 |
| La Jolla Park Coastal Historic District | La Jolla | District | 2024 |
| La Jolla Post Office | San Diego | Building | 2013 |
| La Jolla Women's Club | La Jolla | Building | 1974 |
| Lafayette Hotel | San Diego | Building | 2012 |
| Las Flores Adobe NHL | Camp Pendleton | Building | 1968 |
| Las Flores Estancia | Camp Pendleton | Site | 1993 |
| Las Flores Site | Camp Pendleton | Site | 1975 |
| Lee, Robert E., Hotel | San Diego | Building | 1980 |
| Libby, Charles, House | Oceanside | Building | 1978 |
| Lindstrom House | San Diego | Building | 2001 |
| Long-Waterman House | San Diego | Building | 1976 |
| Marine Corps Recruit Depot Historic District | San Diego | District | 1991 |
| Marston, George W., House | San Diego | Building | 1974 |
| McClintock Storage Warehouse | San Diego | Building | 1980 |
| Medico-Dental Building | San Diego | Building | 1979 |
| Mission Beach Roller Coaster NHL | San Diego | Structure | 1978 |
| Mission Brewery | San Diego | Building | 1989 |
| Mohnike Adobe | San Diego | Building | 2002 |
| Montecito Ranch House | Ramona | Building | 2017 |
| Moylan, Maj. Myles, House | San Diego | Building | 1984 |
| Munk, Walter and Judith, House | San Diego | District | 2021 |
| Naval Air Station, San Diego, Historic District | San Diego | District | 1991 |
| Naval Training Station | San Diego | District | 2001 |
| Oak Grove Butterfield Stage Station NHL | Oak Grove | Building | 1966 |
| Oceanside City Hall and Fire Station | Oceanside | Building | 1989 |
| Old Mission Dam NHL | San Diego | Structure | 1966 |
| Old Point Loma Lighthouse | San Diego | Structure | 1974 |
| Old Town San Diego Historic District | San Diego | District | 1971 |
| Olivenhain Town Meeting Hall | Olivenhain | Building | 1993 |
| Osuna, Juan Maria, Adobe | Rancho Santa Fe | Building | 2017 |
| Panama Hotel | San Diego | Building | 1984 |
| Park Place Methodist Episcopal Church South | San Diego | Building | 1983 |
| PCF 816 (patrol craft fast) | San Diego | Structure | 2018 |
| Peterson, Robert O.-Russell Forester House | San Diego | Building | 2014 |
| PILOT (Pilot Boat) | San Diego | Structure | 2011 |
| Portuguese Chapel of San Diego | San Diego | Building | 2017 |
| Pythias Lodge Building | San Diego | Building | 1981 |
| Ramona Main Street Colonnade | Ramona | Site | 2018 |
| Ramona Town Hall | Ramona | Building | 1994 |
| Rancho De Los Kiotes | Carlsbad | District | 1992 |
| Rancho Guajome Adobe NHL | Vista | Building | 1970 |
| Rancho Santa Fe Land and Improvement Company Office | Rancho Santa Fe | Building | 1991 |
| Red Rest and Red Roost Cottages | La Jolla | Building | 1976 |
| RENOWN (yacht) | San Diego | Structure | 2012 |
| Rice, Lilian Jenette, House | Rancho Santa Fe | Building | 1991 |
| Robinson Hotel | Julian | Building | 1978 |
| Rockwell Field | San Diego | District | 1991 |
| Rosecroft | San Diego | Building | 2003 |
| Rosicrucian Fellowship Temple | Oceanside | District | 1995 |
| Ruiz-Alvarado Ranch Site | San Diego | Site | 1982 |
| San Diego Armed Services YMCA | San Diego | Building | 2007 |
| San Diego Athletic Club | San Diego | Building | 2013 |
| San Diego Civic Center | San Diego | District | 1988 |
| San Diego Fire Department Shops at Station 6 | San Diego | Building | 2015 |
| San Diego Mission Church NHL | San Diego | Building | 1970 |
| San Diego Presidio NHL | San Diego | Site | 1966 |
| San Diego Rowing Club | San Diego | Building | 1979 |
| San Diego State College | San Diego | District | 1997 |
| San Diego Trust and Savings Bank Building | San Diego | Building | 1999 |
| San Diego Veterans' War Memorial Building-Balboa Park | San Diego | Building | 2000 |
| San Luis Rey Mission Church NHL | Oceanside | Building | 1970 |
| Santa Fe Depot | San Diego | Building | 1972 |
| Santa Margarita Ranchhouse | Camp Pendleton | Building | 1971 |
| Scripps, George H., Memorial Marine Biological Laboratory NHL | La Jolla | Building | 1977 |
| Shaffer, Charles A., House | Rancho Santa Fe | Building | 1991 |
| SILVERGATE (FERRY) | San Diego | Structure | 2025 |
| Sorrento Valley Site | San Diego | Site | 1975 |
| Spreckels Theatre Building | San Diego | Building | 1975 |
| St. Matthew's Episcopal Church | National City | Building | 1973 |
| STAR OF INDIA NHL | San Diego | Structure | 1966 |
| Station and General Office, California Southern Railroad | National City | Building | 1996 |
| Sunnyslope Lodge | San Diego | Building | 1999 |
| Sweet, A. H., Residence and Adjacent Small House | San Diego | Building | 1987 |
| Table Mountain District | Jacumba | District | 1983 |
| Talmadge Park Estates Historic District | San Diego | District | 2024 |
| Teacher Training School Building-San Diego State Normal School | San Diego | Building | 1999 |
| Terwilliger, Claude and Florence, House | Rancho Santa Fe | Building | 1991 |
| Thomas House | Escondido | Building | 1992 |
| Torrey Pines Gliderport | San Diego | Site | 1993 |
| Torrey Pines Lodge | San Diego | Building | 1998 |
| Torrey Pines Park Road | San Diego | Structure | 1998 |
| U.S. Courthouse | San Diego | Building | 1975 |
| U.S. Inspection Station/U.S. Custom House | San Ysidro | Building | 1983 |
| University Heights Water Storage and Pumping Station Historic District | San Diego | District | 2013 |
| US Inspection Station-Tecate | Tecate | Building | 1992 |
| US Post Office-Downtown Station | San Diego | Building | 1985 |
| Verlaque, Theophile, House | Ramona | Building | 1991 |
| Villa Montezuma | San Diego | Building | 1971 |
| Warner's Ranch NHL | Warner Springs | Building | 1966 |
| Watts Building | San Diego | Building | 1979 |
| Wiipuk uun'yaw Trail | Mount Laguna | Site | 2017 |
Balboa Park NHL San Diego · District · listed 1977 
Bancroft, Hubert H., Ranchhouse NHL Spring Valley · Building · listed 1966 
BERKELEY NHL San Diego · Structure · listed 1990 
Estudillo House NHL San Diego · Building · listed 1970 
Hotel Del Coronado NHL Coronado · Building · listed 1971 
Mission Beach Roller Coaster NHL San Diego · Structure · listed 1978 
Oak Grove Butterfield Stage Station NHL Oak Grove · Building · listed 1966 
Old Mission Dam NHL San Diego · Structure · listed 1966 
San Diego Mission Church NHL San Diego · Building · listed 1970 
San Diego Presidio NHL San Diego · Site · listed 1966