| Adams Power Plant Transformer House NHL | Niagara Falls | Building | 1975 |
| Ascension Roman Catholic Church Complex | North Tonawanda | District | 2016 |
| Bacon-Merchant-Moss House | Lockport | Building | 2007 |
| Bewley Building | Lockport | Building | 2018 |
| Bixby, Constant Riley W., House | Hartland | Building | 2002 |
| Bond, Col. William M. and Nancy Ralston, House | Lockport | Building | 1995 |
| Bradley, Amzi, Farmstead | Hartland | Building | 2002 |
| Buildings at Niagara and Seventh Streets | Niagara Falls | District | 2019 |
| Buildings on Niagara Street at Fourth Street | Niagara Falls | District | 2022 |
| Carnegie Library | North Tonawanda | Building | 1995 |
| Carter, John, Farmstead | Youngstown | Building | 2007 |
| Chase-Crowley-Keep House | Lockport | Building | 2008 |
| Chase-Hubbard-Williams House | Lockport | Building | 2008 |
| Chilton Avenue-Orchard Parkway Historic District | Niagara Falls | District | 2010 |
| Cold Springs Cemetery | Lockport | Site | 2004 |
| Comstock, Nathan, Jr., House | Lockport | Building | 2011 |
| Conkey House | Lockport | Building | 2003 |
| DAY PECKINPAUGH, (canal motorship) | Lockport | Structure | 2005 |
| Deveaux School Historic District | Niagara Falls | District | 1974 |
| Dick Block, The | North Tonawanda | Building | 2012 |
| District #10 Schoolhouse | Hartland | Building | 2000 |
| Dole House | Lockport | Building | 2003 |
| First Baptist Church | Newfane | Building | 2004 |
| First Presbyterian Church | Niagara Falls | Building | 2014 |
| First Presbyterian Church of Lewiston and Lewiston Village Cemetery | Lewiston | Building | 2019 |
| First Presbyterian Manse | Niagara Falls | Building | 2012 |
| First Unitarian Universalist Church of Niagara | Niagara Falls | Building | 2007 |
| Former Niagara Falls High School | Niagara Falls | Building | 2002 |
| Forsyth-Warren Farm | Lockport | District | 2020 |
| Fort Niagara Light | Youngstown | Building | 1984 |
| Frontier House | Lewiston | Building | 1974 |
| Gibbs House | Lockport | Building | 2003 |
| Hall Apartments | Niagara Falls | Building | 2022 |
| Harrington Colbblestone Farmhouse and Barn Complex | Hartland | Building | 2005 |
| Harrison Radiator Corporation Factory | Lockport | Building | 2021 |
| Herschell-Spillman Motor Company Complex, The | North Tonawanda | Building | 2013 |
| Herschell, Allan, Carousel Factory | North Tonawanda | Building | 1985 |
| High and Locust Streets Historic District | Lockport | District | 2014 |
| Holley-Rankine House | Niagara Falls | Building | 1979 |
| Holy Trinity Roman Catholic Church Complex | Niagara Falls | Building | 2010 |
| Hopkins House | Lockport | Building | 2003 |
| House at 8 Berkley Drive | Lockport | Building | 2009 |
| Jefferson Apartment Building | Niagara Falls | Building | 2005 |
| Lewiston Mound | Lewiston | Site | 1974 |
| Lockport Industrial District | Lockport | District | 1975 |
| Lower Landing Archeological District NHL | Lewiston | Site | 1974 |
| Lower Niagara River Spear Fishing Docks Historic District | Lewiston | District | 2012 |
| Lowertown Historic District | Lockport | District | 1973 |
| Main Street Historic District | Niagara Falls | District | 2021 |
| Maloney House | Lockport | Building | 2003 |
| Marshall, James G., House | Niagara Falls | Building | 2004 |
| Moore, Benjamin C., Mill | Lockport | Building | 1973 |
| Morse Cobblestone Farmhouse | Wilson | Building | 2010 |
| Mount St. Mary's Hospital | Niagara Falls | Building | 2015 |
| Newton, Philo Cobblestone House | Hartland | Building | 2002 |
| Niagara County Courthouse and County Clerk's Office | Lockport | Building | 1997 |
| Niagara Falls Armory | Niagara Falls | Building | 1995 |
| Niagara Falls City Hall | Niagara Falls | Building | 2001 |
| Niagara Falls Public Library | Niagara Falls | Building | 1974 |
| Niagara Falls School District Administration Building | Niagara Falls | Building | 2014 |
| Niagara Power Project Historic District | Lewiston | District | 2017 |
| Niagara Reservation NHL | Niagara Falls | Site | 1966 |
| Niagara, The | Niagara Falls | Building | 2008 |
| North Ridge United Methodist Church | Norh Ridge | Building | 2002 |
| Oakwood Cemetery | Niagara Falls | Site | 2014 |
| Old Fort Niagara-Colonial Niagara Historic District NHL | Youngstown | District | 1966 |
| Oliver, Thomas, House | Lockport | Building | 1998 |
| Park Place Historic District | Niagara Falls | District | 2010 |
| Payne Avenue High School | North Tonawanda | Building | 2019 |
| Pound-Hitchens House | Lockport | Building | 2015 |
| Riviera Theatre | North Tonawanda | Building | 1980 |
| Sacred Heart Roman Catholic Church Complex | Niagara Falls | District | 2019 |
| Sagamore Apartments and Shops, The | Niagara Falls | Building | 2022 |
| Schoellkopf Hall | Niagara Falls | Building | 2023 |
| Schoellkopf Power Station No. 3 Site | Niagara Falls | Site | 2013 |
| Seippel Bakery and Richard Apartments | Niagara Falls | Building | 2018 |
| Sheldon, Hazard H., House | Niagara Falls | Building | 2011 |
| South Junior High School | Niagara Falls | Building | 2016 |
| St. John's Episcopal Church | Youngstown | Building | 1990 |
| St. Mary's Nurses' Residence | Niagara Falls | Building | 2004 |
| Stickney House | Lockport | Building | 2003 |
| Sweeney Estate Historic District | North Tonawanda | District | 2020 |
| Tatler Club | Niagara Falls | Building | 2024 |
| Taylor, William, House | Middleport | Building | 2012 |
| Thirty Mile Point Light | Somerset | District | 1984 |
| Town of Niagara District School No. 2 | Niagara Falls | Building | 2005 |
| U.S. Customhouse | Niagara Falls | Building | 1973 |
| Union Station | Lockport | Building | 1977 |
| United Office Building | Niagara Falls | Building | 2006 |
| US Post Office-Lockport | Lockport | Building | 1989 |
| US Post Office-Middleport | Middleport | Building | 1989 |
| US Post Office-Niagara Falls Main | Niagara Falls | Building | 1989 |
| US Post Office-North Tonawanda | North Tonawanda | Building | 1989 |
| Van Horn Mansion | Newfane | Building | 1991 |
| Walter, Peter D., House | Lockport | Building | 2007 |
| Watson House | Lockport | Building | 2003 |
| White-Pound House | Lockport | Building | 2003 |
| Whitney Mansion | Niagara Falls | Building | 1974 |
| Williams, Johann, Farm | Niagara Falls | Building | 1980 |
Adams Power Plant Transformer House NHL Niagara Falls · Building · listed 1975 
Niagara Reservation NHL Niagara Falls · Site · listed 1966 
Lower Landing Archeological District NHL Lewiston · Site · listed 1974 
Old Fort Niagara-Colonial Niagara Historic District NHL Youngstown · District · listed 1966 
Bacon-Merchant-Moss House Lockport · Building · listed 2007 
Bixby, Constant Riley W., House Hartland · Building · listed 2002 
Bond, Col. William M. and Nancy Ralston, House Lockport · Building · listed 1995 
Bradley, Amzi, Farmstead Hartland · Building · listed 2002 
Carnegie Library North Tonawanda · Building · listed 1995 
Carter, John, Farmstead Youngstown · Building · listed 2007