| Ansco Company Charles Street Factory Buildings | Binghamton | District | 2012 |
| Bennett, Abel, Tract Historic District | Binghamton | District | 2008 |
| Bevier-Wright House | Port Dickinson | Building | 2008 |
| Binghamton City Hall | Binghamton | Building | 1971 |
| Binghamton Railway Company Complex | Binghamton | Building | 2006 |
| Binghamton Theatre | Binghamton | Building | 2008 |
| Broome County Courthouse | Binghamton | Building | 1973 |
| Building at 171-177 Clinton Street | Binghamton | Building | 2002 |
| Bundy, Harlow E., House | Binghamton | Building | 2011 |
| Cameo Theatre | Binghamton | Building | 2022 |
| Chenango Canal Prism and Lock 107 | Chenango Forks | Structure | 2010 |
| Christ Church | Binghamton | Building | 1974 |
| Conklin Town Hall | Conklin | Building | 2006 |
| Court Street Historic District | Binghamton | District | 1984 |
| Drovers Inn and Round Family Residence | Vestal | District | 2010 |
| Dunk, Alfred, House | Binghamton | Building | 1985 |
| Emmanuel Church of the Evangelical Association of Binghamton | Binghamton | Building | 2009 |
| Endicott Square Deal Arch | Endicott | Structure | 2001 |
| Endicott-Johnson Medical Clinic | Binghamton | Building | 2015 |
| First Presbyterian Church of Deposit | Deposit | Building | 2019 |
| Gates, Cyrus, Farmstead | Maine | District | 1999 |
| General Cigar Company-Ansco Camera Factory Building | Binghamton | Building | 2012 |
| Goodwill Theatre | Johnson City | Building | 2000 |
| Grace Episcopal Church | Whitney Point | Building | 1998 |
| Harpursville United Methodist Church | Harpursville | Building | 2006 |
| Hawleyton Methodist Episcopal Church, Old | Hawleyton | Building | 2006 |
| Highland Park Carousel | Endwell | Object | 1992 |
| Hotchkiss, Jedediah, House | Windsor | Building | 1982 |
| Johnson City High School | Johnson City | Building | 2025 |
| Johnson City Historic District | Johnson City | District | 2011 |
| Johnson City Square Deal Arch | Johnson City | Structure | 2001 |
| Johnson, C. Fred, Park Carousel | Johnson City | Object | 1992 |
| Johnson, George F., Recreation Park Carousel | Binghamton | Object | 1992 |
| Johnson, George W., Park Carousel | Endicott | Object | 1992 |
| Jones, Gen. Edward F., House | Binghamton | Building | 2005 |
| Kilmer, Jonas M., House | Binghamton | Building | 2006 |
| Lithuanian National Association Hall | Binghamton | Building | 2015 |
| Main Street Historic District | Binghamton | District | 2021 |
| Maine Central School | Maine | Building | 1998 |
| Marlborough Building | Binghamton | Building | 2008 |
| New York State Inebriate Asylum NHL | Binghamton | Building | 1996 |
| Ouaquaga Lenticular Truss Bridge | Ouaquaga | Structure | 2003 |
| Patterson-Hooper Family Cemetery | Endwell | Site | 2008 |
| Phelps Mansion | Binghamton | Building | 1973 |
| Railroad Terminal Historic District | Binghamton | District | 1986 |
| Riverside Cemetery | Endicott | Site | 2004 |
| Roberson Mansion | Binghamton | Building | 1980 |
| Rose, Robert H., House | Binghamton | Building | 1980 |
| Ross Park Carousel | Binghamton | Object | 1992 |
| Saints Cyril and Methodius Slovak Roman Catholic School | Binghamton | Building | 2007 |
| Sheltered Workshop for the Disabled Building | Binghamton | Building | 2024 |
| South Washington Street Parabolic Bridge | Binghamton | Structure | 1978 |
| State Street-Henry Street Historic District | Binghamton | District | 1986 |
| State Street-Henry Street Historic District (Boundary Increase) | Binghamton | District | 2024 |
| Stone Spillway, National Defense Stockpile Center | Hilcrest | Structure | 2004 |
| Trinity Memorial Church | Binghamton | Building | 1998 |
| United States Post Office and Courthouse | Binghamton | Building | 2020 |
| US Post Office-Endicott | Endicott | Building | 1988 |
| US Post Office-Johnson City | Johnson City | Building | 1989 |
| Vestal Central School | Vestal | Building | 2010 |
| Washingtonian Hall | Endwell | Building | 1996 |
| Wells, J. Stuart, House | Binghamton | Building | 2009 |
| West Endicott Hose Company No. 1 | West Endicott | Building | 2013 |
| West Endicott Park Carousel | Endicott | Object | 1992 |
| Whitmore, John T., House | Binghamton | Building | 1986 |
| Whitney, Henry, House | Whitney Point | Building | 2017 |
| Windsor Village Historic District | Windsor | District | 1980 |
| Your Home Library | Johnson City | Building | 2005 |
New York State Inebriate Asylum NHL Binghamton · Building · listed 1996 
Bennett, Abel, Tract Historic District Binghamton · District · listed 2008 
Bevier-Wright House Port Dickinson · Building · listed 2008 
Binghamton City Hall Binghamton · Building · listed 1971 
Binghamton Railway Company Complex Binghamton · Building · listed 2006 
Binghamton Theatre Binghamton · Building · listed 2008 
Broome County Courthouse Binghamton · Building · listed 1973 
Building at 171-177 Clinton Street Binghamton · Building · listed 2002 
Bundy, Harlow E., House Binghamton · Building · listed 2011 
Chenango Canal Prism and Lock 107 Chenango Forks · Structure · listed 2010