| Allcorn-Kokemoor Farmstead | Brenham | Building | 1998 |
| Applewhite, Isaac, House | Chappell Hill | Building | 1985 |
| Bassett and Bassett Banking House | Brenham | Building | 1983 |
| Baylor University Female Department | Independence | Site | 2024 |
| Baylor University Male Department | Independence | Site | 2024 |
| Becker-Hildebrandt House | Brenham | Building | 1990 |
| Blinn College | Brenham | District | 1990 |
| Blue Bell Creameries Complex | Brenham | Building | 1990 |
| Brenham Downtown Historic District | Brenham | District | 2004 |
| Brenham High School | Brenham | Building | 1990 |
| Brenham High School Gymnasium | Brenham | Building | 1990 |
| Brenham Normal and Industrial College | Brenham | Building | 2026 |
| Brenham School | Brenham | Building | 1990 |
| Brenham Water Works | Brenham | Building | 1990 |
| Brockschmidt-Miller House | Brenham | Building | 1990 |
| Brown, John M., House | Washington | Building | 1975 |
| Browning, W. W., House | Chappell Hill | Building | 1972 |
| Burton Commercial Historic District | Burton | District | 1991 |
| Burton Farmers Gin | Burton | Building | 1991 |
| Burton High School | Burton | Building | 1991 |
| Chappell Hill Circulating Library | Chappell Hill | Building | 1985 |
| Chappell Hill Methodist Episcopal Church | Chappell Hill | Building | 1985 |
| Chappell Hill Public School and Chappell Hill Female College Bell | Chappell Hill | Building | 1985 |
| East Brenham | Brenham | District | 1990 |
| Felder, E. King, House | Chappell Hill | Building | 1985 |
| Gantt-Jones House | Burton | Building | 1979 |
| Giddings-Stone Mansion | Brenham | Building | 1976 |
| Giddings-Wilkin House | Brenham | Building | 1976 |
| Hatfield Plantation | Brenham | Building | 1971 |
| Hodde Drugstore | Burton | Building | 1991 |
| Holle, Edmund, House | Brenham | Building | 1990 |
| Houston, Mrs. Sam, House | Independence | Building | 1970 |
| Hoxey, Asa, House | Independence | Building | 1976 |
| Kneip-Bredthauer House | Burton | Building | 1991 |
| Laas, Dr. Charles, House | Burton | Building | 1991 |
| Lenert, Dr. Robert, House | Brenham | Building | 1990 |
| Main Building, Blinn College | Brenham | Building | 1978 |
| Main Street Historic District | Chappell Hill | District | 1985 |
| Matchett, Edgar, House | Brenham | Building | 1990 |
| Mt. Zion Methodist Church | Brenham | Building | 1990 |
| Neumann, William, House | Burton | Building | 1991 |
| Nienstedt, Herbert, House | Burton | Building | 1991 |
| Nienstedt, William, House | Burton | Building | 1991 |
| Pampell-Day House | Brenham | Building | 1970 |
| Red House | Gay Hill | Building | 1971 |
| Reichardt-Low House | Brenham | Building | 1990 |
| Reue-Eickenhorst House | Brenham | Building | 1995 |
| Rogers, William S., House | Chappell Hill | Building | 1985 |
| Routt, J. R., House | Chappell Hill | Building | 1985 |
| Sanders, William Edward, House | Burton | Building | 1991 |
| Santa Fe Railway Company Freight Depot | Brenham | Building | 1990 |
| Schlenker-Kolwes House | Brenham | Building | 1990 |
| Schlenker, Almot, House | Brenham | Building | 1990 |
| Schmidt House | Brenham | Building | 1990 |
| Schroeder, Fritz Paul and Emma, House | Brenham | Building | 1994 |
| Schuerenberg, F. W., House | Brenham | Building | 1990 |
| Schuerenberg, R. A., House | Brenham | Building | 1990 |
| Seelhorst, W. E., House | Brenham | Building | 1990 |
| Seward Plantation | Independence | District | 2013 |
| Smith, John Sterling, Jr., House | Chappell Hill | Building | 1985 |
| Southern Pacific Railroad Freight Depot | Brenham | Building | 1990 |
| St. Mary's Catholic Church | Brenham | Building | 1990 |
| Stage Coach Inn | Chappell Hill | Building | 1976 |
| Synagogue B'nai Abraham | Brenham | Building | 1990 |
| US Post Office-Federal Building-Brenham | Brenham | Building | 1990 |
| Walker, James, Log House | Brenham | Building | 1989 |
| Washington County Courthouse | Brenham | Building | 1990 |
| Waverly | Chappell Hill | Building | 1983 |
| Wehring Shoe Shop and Residence | Burton | Building | 1991 |
| Wood-Hughes House | Brenham | Building | 1990 |